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SP-B/Surfactant Protein B Rabbit pAb (bs-22341R)  
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產(chǎn)品編號 bs-22341R
英文名稱 SP-B/Surfactant Protein B Rabbit pAb
中文名稱 肺表面活性蛋白B抗體
別    名 18 kDa pulmonary surfactant protein; 18 kDa pulmonary-surfactant protein; 6 kDa protein; Pulmonary surfactant apoprotein PSP B; Pulmonary surfactant associated protein B 18kD; Pulmonary surfactant associated protein B; Pulmonary surfactant associated proteolipid SPL Phe; SFTB3; SFTP3; SFTPB; SFTPB surfactant; Surfactant pulmonary associated protein B; Prosurfactant Protein B; pulmonary surfactant-associated glycoprotein B; proSP B; PSP B; PSPB; PSPB_MOUSE; Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SFTB3; SFTP3; SFTPB; SP B; SPB.  
研究領(lǐng)域 腫瘤  心血管  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SP-B: 141-240/377 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.Homodimer; disulfide-linked. Secreted, extracellular space. Function : Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted, extracellular space, surface film.

Similarity:
Contains 1 saposin A-type domain.
Contains 3 saposin B-type domains.

SWISS:
P50405

Gene ID:
20388

Database links:

Entrez Gene: 6439 Human

Entrez Gene: 20388 Mouse

Omim: 178640 Human

SwissProt: P15781 Cow

SwissProt: P07988 Human

SwissProt: P50405 Mouse

Unigene: 512690 Human

Unigene: 46033 Mouse



肺泡表面活性物質(zhì)B(SP-B)也屬糖結(jié)合蛋白家族,參與肺泡表面活性膜的形成和代謝,除在Ⅱ型細胞中強烈表達外,在細支氣管、支氣管上皮內(nèi)也有灶性表達。SP-B是疏水性蛋白,主要效應(yīng)是促進磷脂吸附和分布到肺泡氣-液交界面,促進磷脂單分子層的形成,只有這種單分子層磷脂才能使表面張力降低到最低水平。
產(chǎn)品圖片
Sample: Lane 1: Lung (Mouse) Lysate at 40 ug Lane 2: Lung (Rat) Lysate at 40 ug Lane 3: Molt-4 (Human) Cell Lysate at 30 ug Lane 4: Hela (Human) Cell Lysate at 30 ug Lane 5: A549 (Human) Cell Lysate at 30 ug Primary: Anti-SP-B/Surfactant Protein B (bs-22
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