| 產(chǎn)品編號(hào) | bsm-51330M |
| 英文名稱 | S100A2 Mouse mAb |
| 中文名稱 | S100A2單克隆抗體 |
| 別 名 | S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 結(jié)合蛋白 細(xì)胞分化 |
| 抗體來(lái)源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | 7G5 |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:20-50,IF=1:20-50,ICC/IF=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 11 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human S100A2 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer. Function: May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth. Subunit: Homodimer. Interacts with FKBP4. Tissue Specificity: A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes. Similarity: Belongs to the S-100 family Contains 2 EF-hand domains. SWISS: P29034.3 Gene ID: 6273 Database links: Entrez Gene: 6273 Human Entrez Gene: 628324 Mouse Omim: 176993 Human SwissProt: P29034 Human Unigene: 516484 Human Unigene: 489562 Mouse |
