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Mouse Anti-THAP11  antibody (bsm-51505M)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bsm-51505M
英文名稱 Mouse Anti-THAP11  antibody
中文名稱 THAP11單克隆抗體
別    名 CTG B43a; CTG B45d; HRIHFB2206; RONIN; THA11_HUMAN; THAP 11; THAP domain containing 11; THAP domain-containing protein 11.  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 S26F1
交叉反應(yīng) Human,Mouse (predicted: Cow)
產(chǎn)品應(yīng)用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human THAP11: 151-250 
亞    型 IgM
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008]

Function:
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.

Subcellular Location:
Nucleus. Cytoplasm. May be regulated by shuttling of the protein between the cytoplasm and nucleus.

Similarity:
Belongs to the THAP11 family.
Contains 1 THAP-type zinc finger.

SWISS:
Q96EK4

Gene ID:
57215

Database links:

Entrez Gene: 539845 Cow

Entrez Gene: 57215 Human

Entrez Gene: 59016 Mouse


SwissProt: A5PKF5 Cow

SwissProt: Q96EK4 Human

SwissProt: Q9JJD0 Mouse




產(chǎn)品圖片
Sample: Lane 1: HepG2 cell lysates Primary: Anti-THAP11 (bsm-51505M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 32 kD
Sample: Lane 1: NIH/3T3 cell lysates Primary: Anti-THAP11 (bsm-51505M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 28 kD
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