| 產(chǎn)品編號(hào) | bsm-51639M |
| 英文名稱 | Mouse Anti-PACSIN2 antibody |
| 中文名稱 | 胞漿磷蛋白PACSIN2單克隆抗體 |
| 別 名 | cytoplasmic phosphoprotein PACSIN2; Moderately similar to h74 gene product; OTTHUMP00000198281; OTTHUMP00000198282; OTTHUMP00000198283; OTTHUMP00000198284; PACN2_HUMAN; protein kinase C and casein kinase substrate in neurons 2; protein kinase C and casein kinase substrate in neurons 2; Protein kinase C and casein kinase substrate in neurons protein 2; Protein kinase C and casein kinase substrate in neurons protein; SDP II; SDPII; Syndapin II. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | H5F12 |
| 交叉反應(yīng) | Human (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 56kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant human PACSIN2 between 250-486 amino acids. |
| 亞 型 | IgG1,k |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Function: May play a role in vesicle formation and transport. Subunit: Homodimer. May form heterooligomers with other PACSINs.Interacts (via NPF motifs) with EHD1 (via EH domain). Interacts with EHD3. Interacts (via the SH3 domain) with MICALL1. Interacts with RAC1. Interacts (via SH3 domain) with DNM1, SYN1, SYNJ1 and WASL. Interacts with CAV1. Interacts with TRPV4. Subcellular Location: Cytoplasmic vesicle. Vesicle-like cytoplasmic distribution. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). Similarity: Belongs to the PACSIN family. Contains 1 FCH domain. Contains 1 SH3 domain. SWISS: Q9UNF0 Gene ID: 11252 Database links: Entrez Gene: 11252 Human Entrez Gene: 23970 Mouse SwissProt: Q9UNF0 Human SwissProt: Q9WVE8 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Daudi cell lysates
Lane 2: PC-3 cell lysates
Lane 3: Human brain tissue lysates
Lane 4: Mouse brain tissue lysates
Primary: Anti-PACSIN2 (bsm-51639M) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 58 kD
|
