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Mouse Anti-ADCYAP1  antibody (bsm-51713M)  
~~~促銷代碼KT202411~~~
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產品編號 bsm-51713M
英文名稱 Mouse Anti-ADCYAP1  antibody
中文名稱 ADCYAP1單克隆抗體
別    名 Adenylate Cyclase Activating Polypeptide 1 (Pituitary); Prepro-PACAP; PACAP; Pituitary Adenylate Cyclase Activating Polypeptide; PRP-48; PACAP27; PACAP38; ADCYAP1; PACA_HUMAN;   
研究領域 細胞生物  神經生物學  細胞凋亡  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 G8R3
交叉反應 Recombinant protein (predicted: Human)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 19kDa
細胞定位 細胞外基質 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human ADCYAP1 
亞    型 IgG1,Κ
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Function:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

Subunit:
Interacts with ADCYAP1R1 (via N-terminal extracellular domain).

Subcellular Location:
Extracellular region or secreted

Similarity:
Belongs to the glucagon family.

SWISS:
P18509

Gene ID:
116

Database links:

Entrez Gene: 116 Human

SwissProt: P18509 Human



產品圖片
Sample: Lane 1: ADCYAP1 recombinant protein Primary: Anti-ADCYAP1 (bsm-51713M) at 1/8000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 19 kD Observed band size: 19 kD
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