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Rabbit Anti-IL-1 beta  antibody (bsm-52727R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
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產(chǎn)品編號(hào) bsm-52727R
英文名稱 Rabbit Anti-IL-1 beta  antibody
中文名稱 白介素1β/IL-1β重組兔單抗
別    名 IL1B_HUMAN; Interleukin-1 beta; interleukin 1 beta; IL1F2; IL-1 beta; Catabolin; IL-1; IL1F2; IL1beta; IL1-BETA; IL-1beta; IL-1 Beta; IL-1β; IL1β; IL-1B; IL1B;  IL-1B; IL-1 ?; IL-1-?; IL-1 ?;
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  糖蛋白  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號(hào) 1T3
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-1 beta 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 0.05% BSA, 40% Glycerol, 0.02% Proclin300.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

SWISS:
P01584

Gene ID:
3553

產(chǎn)品圖片
THP-1 (H) cells were treated with or without TPA (80nM) for 24h,then treated with (100ng/ml) lipopolysaccharide (LPS) for 6h, then with (300ng/ml) Brefeldin A added after 3h,25 μg total protein per lane of cell lysates (see on figure) probed with IL-1 beta monoclonal antibody, unconjugated (bsm-52727R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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