| 產(chǎn)品編號 | bsm-43124M |
| 英文名稱 | Mouse Anti-IGFBP3 antibody |
| 中文名稱 | 胰島素樣生長因子結(jié)合蛋白3單克隆抗體 |
| 別 名 | IBP3_HUMAN; Insulin-like growth factor-binding protein 3; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IBP3; BP-53; |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 交叉反應(yīng) | Human,Rat (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 32kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 免 疫 原 | Recombinant human IGFBP3 protein |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | PBS，pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Subcellular Location: Secreted. Tissue Specificity: Expressed by most tissues. Present in plasma. Post-translational modifications: Phosphorylation sites are present in the extracelllular medium. Similarity: Contains 1 IGFBP N-terminal domain. Contains 1 thyroglobulin type-1 domain. SWISS: P17936 Gene ID: 3486 Database links: Entrez Gene: 3486 Human Entrez Gene: 16009 Mouse SwissProt: P17936 Human SwissProt: P47878 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Recombinant human IGFBP3 protein, His (HEK293)(bs-43124P)
Primary: Anti-IGFBP3(bsm-43124M) at 1/1000 dilution
Secondary: Alexa Fluor 790 AffiniPure Goat Anti-Mouse IgG, light chain specific
Predicted band size: 32 kDa
Observed band size: 47 kDa
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