| 產(chǎn)品編號(hào) | V0102-HRP |
| 英文名稱 | CRP |
| 中文名稱 | HRP標(biāo)記的C-反應(yīng)蛋白單克隆抗體 |
| 別 名 | C-reactive protein; C Reactive Protein; C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1. C反應(yīng)蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated in innate immunity. CRP binds to ligands containing phosphocholine, SAP binds to amyloid fibrils, DNA, chromatin, fibronectin, C4-binding proteins and glycosaminoglycans. "Long" pentraxins have N-terminal extensions to the common pentraxin domain; one group, the neuronal pentraxins, may be involved in synapse formation and remodeling, and they may also be able to form heteromultimers. C反應(yīng)蛋白 CRP（C-reactive protin）是與C性肺炎球菌的多糖起反應(yīng)的一種蛋白，在某些細(xì)菌的感染過(guò)程中出現(xiàn)在血漿中。 CRP是在一些病理性情況下出現(xiàn)于病人血清中的一種糖蛋白，特別是在伴有肯炎癥和組織壞死疾病的急性期。血清中出現(xiàn)的這種異常蛋白能和肺炎C-多糖體發(fā)生沉淀反應(yīng)，當(dāng)疾病好轉(zhuǎn)或緩解時(shí)，CRP減低或消失。 臨床意義: (1)各種急性化膿性炎癥、菌血癥、組織壞死(心肌梗塞、手術(shù)、嚴(yán)重創(chuàng)傷、燒傷等)、惡性腫瘤、結(jié)締組織病、腎移殖后急性排異反應(yīng)、急性風(fēng)濕熱、風(fēng)濕性關(guān)節(jié)炎、類風(fēng)濕性關(guān)節(jié)炎、心 |
