| 產(chǎn)品編號(hào) | bsm-63295R |
| 英文名稱 | IL-22 Recombinant Rabbit mAb |
| 中文名稱 | 白介素-22重組兔單抗 |
| 別 名 | IL21; Il22; ILD110; ILTIF; interleukin 21; Interleukin 22; TIFa; TIFIL23; zcyto18. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 7C16 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測(cè)分子量 | 14 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL 22 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Cytokine that plays a critical role in modulating tissue responses during inflammation.Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage.Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. SWISS: Q9GZX6 Gene ID: 50616 IL-22是白介素-10家族的成員,主要是由激活的T 淋巴細(xì)胞產(chǎn)生的一類重要的細(xì)胞因子,除了在Th17細(xì)胞中高表達(dá)之外，在NK和NKT等細(xì)胞中也有表達(dá),在組織損傷修復(fù)以及牛皮癬、肝炎、肺炎、腸炎等慢性炎癥中發(fā)揮重要作用.IL-22是繼IL-6和IL-10之后又一個(gè)參與炎癥反應(yīng)和代謝調(diào)控的細(xì)胞因子，IL-22有可能成為干預(yù)脂肪肝發(fā)生發(fā)展的新方法。 |
