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Rabbit Anti-SDCCAG8/Biotin Conjugated antibody (bs-7011R-Bio)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-7011R-Bio
英文名稱(chēng)1 Rabbit Anti-SDCCAG8/Biotin Conjugated antibody
中文名稱(chēng) 生物素標(biāo)記的結(jié)腸癌抗原8抗體
別    名 Antigen NY CO 8; CCCAP; Centrosomal colon cancer autoantigen protein; HSPC085; NPHP10 gene; NY-CO-8; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7 gene; SDCG8_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞類(lèi)型標(biāo)志物  腫瘤細(xì)胞生物標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83 kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDCCAG8
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The exact function of SDCCAG8 remains unknown. It is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.

Function:
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.

Subunit:
Homodimer (By similarity). Interacts with OFD1; the interaction is direct. Interacts with FAM161A.

Subcellular Location:
Isoform 2: Cytoplasm.

Tissue Specificity:
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.

DISEASE:
Defects in SDCCAG8 are the cause of Senior-Loken syndrome type 7 (SLSN7) [MIM:613615]. SLSN7 is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.

Database links:
UniProtKB/Swiss-Prot: Q86SQ7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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