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Rabbit Anti-BCAS1/Gold Conjugated antibody (bs-11462R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11462R-Gold
英文名稱1 Rabbit Anti-BCAS1/Gold Conjugated antibody
中文名稱 膠體金標記的乳腺癌相關(guān)蛋白1抗體
別    名 NABC1; AIBC 1; AIBC1; Amplified and overexpressed in breast cancer; BCAS 1; BCAS1; BCAS1_HUMAN; Breast carcinoma amplified sequence 1; Breast carcinoma-amplified sequence 1; Novel amplified in breast cancer 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BCAS1 (542-584aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008]

Function:
Expressed in brain and prostate, and at lower levels in testis, intestine and colon. Overexpressed in most breast cancer cell lines and down-regulated in some colorectal tumors.

Subunit:
Homodimer. May interact with DYNLL1 and DYNLL2

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in brain and prostate, and at lowerlevels in testis, intestine and colon. Overexpressed in most breastcancer cell lines and down-regulated in some colorectal tumors.

Database links:

Entrez Gene: 8537 Human

Omim: 602968 Human

SwissProt: O75363 Human

Unigene: 728940 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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