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Rabbit Anti-TNFSF4/BF594 Conjugated antibody (bs-2463R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2463R-BF594
英文名稱1 Rabbit Anti-TNFSF4/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的腫瘤壞死因子配體超家族成員4抗體
別    名 CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞表面分子  淋巴細(xì)胞  t-淋巴細(xì)胞  細(xì)胞因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat TNFSF4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]

Function:
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

Subunit:
Homotrimer (Probable).

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Detected in T-cell lines, but not in a macrophage cell line.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 7292 Human

Entrez Gene: 22164 Mouse

Entrez Gene: 89814 Rat

Omim: 603594 Human

SwissProt: P23510 Human

SwissProt: P43488 Mouse

SwissProt: Q9Z2P3 Rat

Unigene: 181097 Human

Unigene: 4994 Mouse

Unigene: 30043 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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