產(chǎn)品編號(hào) | bs-0124R-Gold |
英文名稱1 | Rabbit Anti-Calcitonin receptor/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的降鈣素受體抗體 |
別 名 | Calcitonin receptor precursor; Calcr; CRT; CT R; CTR; CTR1; CALCR_MOUSE; CT-R; CALCR_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 G蛋白偶聯(lián)受體 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat, (predicted: Mouse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 53kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse Calcitonin receptor |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] Function: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Subunit: Interacts with GPRASP2. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. Database links: Entrez Gene: 799 Human Entrez Gene: 12311 Mouse Omim: 114131 Human SwissProt: P30988 Human SwissProt: Q60755 Mouse Unigene: 489127 Human Unigene: 4642 Mouse Unigene: 10062 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 降鈣素受體(Calcitonin receptor,CT-R)是G蛋白偶聯(lián)受體,有兩種受體亞型,CT-R可與多種配體結(jié)合,如CGRP、Amylin、Am等。CT-R在破骨細(xì)胞中含量最高,也存在于腎等多種器官組織內(nèi)。 |