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Rabbit Anti-R-cadherin/PE-Cy7 Conjugated antibody (bs-3675R-PE-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3675R-PE-Cy7
英文名稱1 Rabbit Anti-R-cadherin/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的R-鈣粘附分子抗體
別    名 Cadherin 4; Cadherin4; Cadherin-4 CDH4; R CAD; Retinal Cadherin.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  激酶和磷酸酶  細胞粘附分子  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human R-cadherin(423-475aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cadherins constitute a superfamily of calcium-dependent intercellular adhesion molecules and are thought to play a role in cell recognition and segregation, morphogenetic regulation, and tumor suppression. R Cadherin is expressed mainly in the brain but is also found in other tissues.

Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed mainly in brain but also found in other tissues.

Similarity:
Contains 5 cadherin domains.

Database links:

Entrez Gene: 1002 Human

Entrez Gene: 12561 Mouse

Entrez Gene: 114588 Rat

Omim: 603006 Human

SwissProt: P55283 Human

SwissProt: P39038 Mouse

SwissProt: Q80ZV4 Mouse

SwissProt: Q63149 Rat

Unigene: 473231 Human

Unigene: 598638 Human

Unigene: 184711 Mouse

Unigene: 382094 Mouse

Unigene: 392073 Mouse

Unigene: 214089 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

R-鈣粘附分子,是依賴鈣離子的細胞間糖蛋白粘附分子的一種,主要是參與細胞間同源性粘附、調控和介導細胞間相互反應,在腫瘤的遷移、分化中起到一定的作用。在腦組織中表達外,其他組織中已有定位。
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