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Rabbit Anti-SEPT10/PE-Cy5 Conjugated antibody (bs-7770R-PE-Cy5)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-7770R-PE-Cy5
英文名稱(chēng)1 Rabbit Anti-SEPT10/PE-Cy5 Conjugated antibody
中文名稱(chēng) PE-Cy5標(biāo)記的細(xì)胞分化蛋白SEPT10抗體
別    名 SEPT 10; SEPT-10; Septin 10; Septin-10; Septin 10; SEP10_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEPT10
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The SEPT10 gene encodes a member of the septin family of cytoskeletal proteins which have GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms.

Function:
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).

Subunit:
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Note=Using a GFP-fusion protein, detected in the nucleus (PubMed:12711328).

Tissue Specificity:
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.

Similarity:
Belongs to the septin family.

Database links:

Entrez Gene: 151011 Human

Entrez Gene: 103080 Mouse

Omim: 611737 Human

SwissProt: Q9P0V9 Human

SwissProt: Q8C650 Mouse

Unigene: 469615 Human

Unigene: 346842 Mouse

Unigene: 397041 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

SEPTIN(SEPT)家族是細(xì)胞骨架蛋白的一種,具有GTPase的活性。經(jīng)研究發(fā)現(xiàn),SEPT參與細(xì)胞核分裂、細(xì)胞膜的運(yùn)輸以及構(gòu)成細(xì)胞骨架。
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