| 產(chǎn)品編號 | bs-0337R-AP |
| 英文名稱1 | Rabbit Anti-Myelin Protein Zero/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的外周髓磷脂P0蛋白/P0蛋白抗體 |
| 別 名 | peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein; CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Dog, (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P0 protein (209-228aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein. Subunit: Homodimer and homotetramer. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Found only in peripheral nervous system Schwann cells. Similarity: Belongs to the myelin P0 protein family. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Database links: Entrez Gene: 4359 Human Entrez Gene: 17528 Mouse Omim: 159440 Human SwissProt: P25189 Human SwissProt: P27573 Mouse Unigene: 591486 Human Unigene: 93883 Human Unigene: 9986 Mouse UniProtKB/Swiss-Prot: P25189.1
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 成熟的周圍神經(jīng)系統(tǒng)髓鞘主要的蛋白為P0蛋白，分子量28KDa，它具有單個跨膜區(qū)，是IgG超家族的成員之一。 |
