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Rabbit Anti-SP-B/Surfactant Protein B/AP Conjugated antibody (bs-1034R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1034R-AP
英文名稱 Rabbit Anti-SP-B/Surfactant Protein B/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的肺表面活性蛋白B抗體
別    名 18 kDa pulmonary surfactant protein; 18 kDa pulmonary-surfactant protein; 6 kDa protein; Pulmonary surfactant apoprotein PSP B; Pulmonary surfactant associated protein B 18kD; Pulmonary surfactant associated protein B; Pulmonary surfactant associated proteolipid SPL Phe; SFTB3; SFTP3; SFTPB; SFTPB surfactant; Surfactant pulmonary associated protein B; Prosurfactant Protein B; pulmonary surfactant-associated glycoprotein B; proSP B; PSP B; PSPB; PSPB_MOUSE; Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SFTB3; SFTP3; SFTPB; SP B; SP-B; SPB.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Mouse, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SP-B
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.Homodimer; disulfide-linked. Secreted, extracellular space.

Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted, extracellular space, surface film.

Similarity:
Contains 1 saposin A-type domain.
Contains 3 saposin B-type domains.

Database links:

Entrez Gene: 6439 Human

Entrez Gene: 20388 Mouse

Omim: 178640 Human

SwissProt: P15781 Cow

SwissProt: P07988 Human

SwissProt: P50405 Mouse

Unigene: 512690 Human

Unigene: 46033 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肺泡表面活性物質(zhì)B(SP-B)也屬糖結(jié)合蛋白家族,參與肺泡表面活性膜的形成和代謝,除在Ⅱ型細(xì)胞中強(qiáng)烈表達(dá)外,在細(xì)支氣管、支氣管上皮內(nèi)也有灶性表達(dá)。SP-B是疏水性蛋白,主要效應(yīng)是促進(jìn)磷脂吸附和分布到肺泡氣-液交界面,促進(jìn)磷脂單分子層的形成,只有這種單分子層磷脂才能使表面張力降低到最低水平。
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