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Rabbit Anti-TALLA-1/PE-Cy5.5 Conjugated antibody (bs-9416R-PE-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-9416R-PE-Cy5.5
英文名稱1 Rabbit Anti-TALLA-1/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的T細(xì)胞急性淋巴母細(xì)胞白血病相關(guān)抗原1抗體
別    名 CD231 antigen; Cell surface glycoprotein A15; Membrane component X chromosome surface marker 1; T cell acute lymphoblastic leukemia associated antigen 1; TALLA 1; TALLA1; Tetraspanin 7; Tetraspanin-7; Transmembrane 4 superfamily member 2; Tspan 7; TSN7_HUMAN; Tspan-7; TALLA-1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Tetraspanin-7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. TSPAN7 (tetraspanin 7), also known as MXS1 (membrane component chromosome X surface marker 1) or TM4SF2 (transmembrane 4 superfamily member 2), is a 249 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family of transmembrane proteins. TSPAN7 is believed to play a role in cell motility and cell proliferation. The gene that encodes TSPAN7 maps to human chromosome X and defects in this gene are a cause of mental retardation X-linked type 58 (MRX58), which is characterized by dramatically below average general intellectual functioning.

Function:
May be involved in cell proliferation and cell motility.

Subunit:
Interacts with herpes simplex virus 1 (HHV-1) UL35.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients.

DISEASE:
Defects in TSPAN7 are the cause of mental retardation X-linked type 58 (MRX58) [MIM:300210]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Database links:
UniProtKB/Swiss-Prot: P41732.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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