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Rabbit Anti-SNX25/BF488 Conjugated antibody (bs-4070R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4070R-BF488
英文名稱 Rabbit Anti-SNX25/BF488 Conjugated antibody
中文名稱 BF488標記的分揀微管連接蛋白抗體
別    名 SBBI31; Sorting nexin-25; AI661919; FLJ23161; Gm1699; Gm173; MSTP043; SNX25; SNX25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  信號轉導  轉錄調(diào)節(jié)因子  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNX25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNX25 (sorting nexin 25), also known as SBBI31 or MSTP043, is an 840 amino acid protein suggested to function in several stages of intracellular trafficking. A member of the sorting nexin family, SNX25 contains one PX (phox homology) domain, an RGS domain and one PXA domain.

Function:
May be involved in several stages of intracellular trafficking

Subcellular Location:
Endosome membrane; Peripheral membrane protein. Note=Detected in endosome-derived secreted vesicles (exosomes) from malignant pleural effusions.

Similarity:
Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Contains 1 PXA domain.
Contains 1 RGS domain.

Database links:

Entrez Gene: 83891 Human

Entrez Gene: 102141 Mouse

Entrez Gene: 306471 Rat

SwissProt: Q9H3E2 Human

SwissProt: Q3ZT31 Mouse

Unigene: 369091 Human

Unigene: 267258 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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