產(chǎn)品編號 | bs-14009R-Gold |
英文名稱1 | Rabbit Anti-COX6B2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的細胞色素C氧化酶蛋白6B2抗體 |
別 名 | Cancer/testis antigen 59; COX VIb-2; Cox6b2; COXVIb-2; COXVIb2; CT59; CX6B2_HUMAN; Cytochrome c oxidase subunit 6B2; Cytochrome c oxidase subunit VIb; Cytochrome c oxidase subunit VIb isoform 2; cytochrome c oxidase subunit VIb polypeptide 2 (testis); Cytochrome c oxidase subunit VIb testes specific; Cytochrome c oxidase subunit VIb, testis-specific isoform; FLJ46422; MGC119094; testis-specific isoform. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細胞生物 信號轉(zhuǎn)導(dǎo) 細胞類型標(biāo)志物 新陳代謝 鋅指蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 11kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human COX6B2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines. Function: Connects the two COX monomers into the physiological dimeric form. Subcellular Location: Mitochondrion intermembrane space. Tissue Specificity: Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines. Similarity: Belongs to the cytochrome c oxidase subunit 6B family. Database links: Entrez Gene: 125965 Human Entrez Gene: 333182 Mouse SwissProt: Q6YFQ2 Human SwissProt: Q80ZN9 Mouse Unigene: 550544 Human Unigene: 29625 Mouse Unigene: 97699 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |