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Rabbit Anti-TRH/BF647 Conjugated antibody (bs-10593R-BF647)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-10593R-BF647
英文名稱1 Rabbit Anti-TRH/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的促甲狀腺素釋放激素抗體
別    名 Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF; TRH_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  內(nèi)分泌病  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated human TRH (pGlu-His-Pro-Amide)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013].
(L-Pyroglutamyl-L-histidyl-L-prolinamide)pGlu-His-Pro Amide, C18H26N6O6


Function:
Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets.

Subcellular Location:
Secreted.

Tissue Specificity:
Hypothalamus. Expressed in the hair follicle epithelium (at protein level).

Similarity:
Belongs to the TRH family.

Database links:

Entrez Gene: 7200 Human

Entrez Gene: 22044 Mouse

Entrez Gene: 25569 Rat

Omim: 275120 Human

SwissProt: P20396 Human

SwissProt: Q62361 Mouse

SwissProt: P01150 Rat

Unigene: 1363 Mouse

Unigene: 22 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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