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Rabbit Anti-NAV3/AP Conjugated antibody (bs-12151R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12151R-AP
英文名稱1 Rabbit Anti-NAV3/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的神經(jīng)元引導(dǎo)蛋白3抗體
別    名 KIAA0938; NAV 3; NAV3; NAV3_HUMAN; Neuron navigator 3; POMFIL1; Pore membrane and/or filament-interacting-like protein 1; Steerin 3; Steerin-3; STEERIN3; Unc 53 homolog 3; Unc-53 homolog 3; unc53H3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Horse, Sheep, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 255kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAV3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.

Function:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.

Subcellular Location:
Nucleus outer membrane.

Tissue Specificity:
Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.

DISEASE:
Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2).

Similarity:
Sequence similarities; Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.

Database links:

Entrez Gene: 89795 Human

Entrez Gene: 260315 Mouse

Entrez Gene: 314814 Rat

Omim: 611629 Human

SwissProt: Q8IVL0 Human

SwissProt: Q80TN7 Mouse

Unigene: 655301 Human

Unigene: 225050 Mouse

Unigene: 394160 Mouse

Unigene: 461280 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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