產(chǎn)品編號 | bs-12528R-BF350 |
英文名稱1 | Rabbit Anti-ARPC4/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的肌動(dòng)蛋白相關(guān)蛋白2/3亞型4抗體 |
別 名 | Actin related protein 2/3 complex subunit 4; Actin related protein 2/3 complex subunit 4 20 kD; Actin related protein 2/3 complex subunit 4 20kDa; Actin-related protein 2/3 complex subunit 4; ARC20; Arp2/3 complex 20 kDa subunit; Arp2/3 protein complex subunit p20; ARPC 4; ARPC4; ARPC4_HUMAN; MGC13544; OTTHUMP00000165252; OTTHUMP00000207520; p20 Arc; p20-ARC; p20ARC. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 結(jié)合蛋白 細(xì)胞骨架 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Cow, Rabbit, Zebrafish, Sheep, Xenopus laevis) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 20kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ARPC4/p20-ARC |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]. Function: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Subunit: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Subcellular Location: Cytoplasm; cytoskeleton. Cell projection. Similarity: Belongs to the ARPC4 family. Database links: Entrez Gene: 10093 Human Entrez Gene: 68089 Mouse Entrez Gene: 114456 Zebrafish Omim: 604226 Human SwissProt: P59998 Human SwissProt: P59999 Mouse Unigene: 323342 Human Unigene: 289306 Mouse Unigene: 472172 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |