| 產(chǎn)品編號(hào) | bs-13395R-Gold |
| 英文名稱1 | Rabbit Anti-Glutaredoxin 5/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的谷氧還蛋白5抗體 |
| 別 名 | C14orf87; Chromosome 14 open reading frame 87; FLB4739; GLRX 5; Glrx5; GLRX5_HUMAN; Glutaredoxin 5 homolog; Glutaredoxin related protein 5; Glutaredoxin-related protein 5; Glutaredoxin5; GRX5; MGC14129; mitochondrial; Monothiol glutaredoxin-5; PRO1238. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Glutaredoxin 5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010] Function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. Subunit: Homodimer. Subcellular Location: Mitochondrion. DISEASE: Defects in GLRX5 are a cause of anemia sideroblastic pyridoxine-refractory autosomal recessive (PRARSA) [MIM:205950]. A form of sideroblastic anemia not responsive to pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus. Similarity: Belongs to the glutaredoxin family. Monothiol subfamily. Contains 1 glutaredoxin domain. Database links: Entrez Gene: 51218 Human Entrez Gene: 73046 Mouse Omim: 609588 Human SwissProt: Q86SX6 Human SwissProt: Q80Y14 Mouse Unigene: 532683 Human Unigene: 728210 Human Unigene: 29128 Mouse Unigene: 104008 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
