| 產(chǎn)品編號(hào) | bs-10504R-Gold |
| 英文名稱1 | Rabbit Anti-valyl tRNA/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的纈氨酰-tRNA合成酶抗體 |
| 別 名 | SYVM_HUMAN; Valine--tRNA ligase, mitochondrial; Valyl-tRNA synthetase; ValRS; Valyl-tRNA synthetase-like; valyl tRNA; VARS2; KIAA1885; VARS2L; VARSL. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 合成與降解 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 115kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human vars2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: ValRS (valyl-tRNA synthetase), also known as Protein G7a, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ValRS joins Val to tRNA(Val) at its synthetic active site. At its CP1 editing active site, ValRS hydrolyzes or deacylates tRNA(Thr) that is incorrectly joined to Val. ValRS forms aggregates with EF-1 (elongation factor 1) and, via this complex, catalyzes the aminoacylation of tRNA and its transfer to EF-1. In addition, ValRS may be regulated by PKC-dependent phosphorylation. Subcellular Location: Mitochondrion (Potential). Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. Database links: Entrez Gene: 7407 Human Omim: 192150 Human SwissProt: P26640 Human Unigene: 520026 Human Unigene: 12314 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
