| 產(chǎn)品編號(hào) |
bs-10970R-Gold |
| 英文名稱1 |
Rabbit Anti-ANGPTL6/Gold Conjugated antibody
|
| 中文名稱 |
膠體金標(biāo)記的血管生成素相關(guān)蛋白6抗體 |
| 別 名 |
ARP5; AGF; Angiopoietin like 6; Angiopoietin like Protein 6; Angiopoietin related Growth Factor; Angiopoietin related protein 5; Angiopoietin-like protein 6; Angiopoietin-related growth factor; Angiopoietin-related protein 5; Angiopoietin-related protein 6; ANGL6_HUMAN; Angptl6; ARP5. |
| 規(guī)格價(jià)格 |
100ul/2980元
購買 大包裝/詢價(jià) |
| 說 明 書 |
100ul（10nm 15nm 35nm）
|
| 研究領(lǐng)域 |
心血管 細(xì)胞生物 血管內(nèi)皮細(xì)胞 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Horse, Rabbit, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
49kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
0.4mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human ANGPTL6 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 |
Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background:
Angptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract obesity by increasing energy expenditure. Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Function:
May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
Subcellular Location:
Secreted (Probable).
Similarity:
Contains 1 fibrinogen C-terminal domain.
Database links:
Entrez Gene: 83854 Human
Entrez Gene: 70726 Mouse
Omim: 609336 Human
SwissProt: Q8NI99 Human
SwissProt: Q8R0Z6 Mouse
Unigene: 712850 Human
Unigene: 34019 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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