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Rabbit Anti-SLC6A18/APC Conjugated antibody (bs-20229R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20229R-APC
英文名稱1 Rabbit Anti-SLC6A18/APC Conjugated antibody
中文名稱 APC標記的溶質載體家族6成員18抗體
別    名 S6A18_HUMAN; Sodium-dependent neutral amino acid transporter B(0)AT3; Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC6A18
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Functions as a sodium and chloride-dependent neutral amino acid transporter. {ECO:0000250}.

Subunit:
Associates with TMEM27. TMEM27 association is required for functional expression in kidney. {ECO:0000250}.

Subcellular Location:
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Tissue Specificity:
Abundantly expressed in kidney, but not in intestine. {ECO:0000269|PubMed:15286787}.

DISEASE:
Note=Genetic variations in SLC6A18 might contribute to the disease phentotype in some individuals with iminoglycinuria or hyperglycinuria, that carry variants in SLC36A2, SLC6A19 or SLC6A20.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily. {ECO:0000305}.

Database links:

Entrez Gene: 348932 Human

Entrez Gene: 22598 Mouse

Entrez Gene: 29323 Rat

Omim: 610300 Human

SwissProt: Q96N87 Human

SwissProt: O88576 Mouse

SwissProt: Q62687 Rat

Unigene: 213284 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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