產(chǎn)品編號(hào) | bs-10690R-PE-Cy7 |
英文名稱1 | Rabbit Anti-phospho-Ephrin B1 (Tyr317)/PE-Cy7 Conjugated antibody |
中文名稱 | PE-Cy7標(biāo)記的磷酸化Ephrin B1抗體 |
別 名 | phospho-Ephrin B1 (phospho Y317); Ephrin B (phospho Y317); p-Ephrin B (phospho Y317); phospho-Ephrin B1 (Tyr317); phospho-Ephrin B2(Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
產(chǎn)品類型 | 磷酸化抗體 |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 生長(zhǎng)因子和激素 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 34kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human Ephrin B1 around the phosphorylation site of Tyr317 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. Subunit: Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein. Tissue Specificity: Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments. Post-translational modifications: Membrane; single pass type I membrane protein. Similarity: Belongs to the ephrin family. Contains 1 ephrin RBD (ephrin receptor-binding) domain. Database links: Entrez Gene: 1947 Human Entrez Gene: 1948 Human Entrez Gene: 13641 Mouse Entrez Gene: 13642 Mouse Omim: 300035 Human Omim: 600527 Human SwissProt: P52799 Human SwissProt: P98172 Human SwissProt: P52795 Mouse SwissProt: P52800 Mouse Unigene: 144700 Human Unigene: 149239 Human Unigene: 44398 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |