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Rabbit Anti-NKIRAS2/BF647 Conjugated antibody (bs-19265R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19265R-BF647
英文名稱1 Rabbit Anti-NKIRAS2/BF647 Conjugated antibody
中文名稱 BF647標記的核轉錄因子κB抑制作用Ras樣2蛋白抗體
別    名 DKFZP434N1526; I kappa B interacting Ras like protein 2; I-kappa-B-interacting Ras-like protein 2; Kappa B Ras protein 2; Kappa B-Ras protein 2; KappaB Ras2; KappaB-Ras2; KBRAS 2; KBRAS2; KBRS2_HUMAN; MGC74742; NF kappa B inhibitor interacting Ras like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras like 2; NFKB inhibitor interacting Ras like protein 2; NKIRAS 2; NKIRAS2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  表觀遺傳學  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NKIRAS2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

Database links:

Entrez Gene: 509053 Cow

Entrez Gene: 28511 Human

Entrez Gene: 71966 Mouse

Entrez Gene: 287707 Rat

Omim: 604497 Human

SwissProt: Q9NYR9 Human

SwissProt: Q9CR56 Mouse

Unigene: 632252 Human

Unigene: 274734 Mouse

Unigene: 90866 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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