| 產(chǎn)品編號(hào) | bs-16057R-BF488 |
| 英文名稱1 | Rabbit Anti-FCF1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的FCF1蛋白抗體 |
| 別 名 | Bka; C14orf111; CGI 35; Fcf1; FCF1 small subunit (SSU) processome component homolog (S. cerevisiae); FCF1_HUMAN; rRNA processing protein FCF1 homolog; rRNA-processing protein FCF1 homolog. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FCF1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Ribosomes are the organelles that catalyze protein synthesis. Ribosomes consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. FCF1 is a 198 amino acid protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. The gene encoding FCF1 maps to human chromosome 14, which contains about 700 genes and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder α1-antitrypsin deficiency. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. Function: Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Subcellular Location: Nucleus > nucleolus. Similarity: Belongs to the UTP23/FCF1 family. FCF1 subfamily. Contains 1 PINc domain. Database links: Entrez Gene: 51077 Human Entrez Gene: 100507758 Human SwissProt: Q9Y324 Human Unigene: 579828 Human Unigene: 711584 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
