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Rabbit Anti-TRAPPC4/AP Conjugated antibody (bs-16585R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16585R-AP
英文名稱1 Rabbit Anti-TRAPPC4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的SBDN蛋白抗體
別    名 CGI 104; Hematopoietic stem/progenitor cell protein 172; HSPC172; PTD009; SBDN; TPPC4_HUMAN; Synbindin; Trafficking protein particle complex subunit 4; TRAPPC4; TRS23; TRS23 homolog.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAPPC4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
TRAPPC4 is a postsynaptic protein belonging to the TRAPPC4 subfamily of the TRAPP small subunits family of proteins. Expressed in neurons and localizing to the Golgi apparatus, TRAPPC4 is believed to be involved in vesicular transport from the endoplasmic reticulum (ER) to the Golgi, functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Similar to other proteins involved in vesicular transport or synaptic function, TRAPPC4 contains a nonclassical PDZ domain, a TRAPPC1-like domain and a C-terminus that is similar to a short segment of RyR. Via its nonclassical PDZ domain, TRAPPC4 binds to the C-terminal EFYA motif of Syndecan-2, suggesting that TRAPPC4 may play an important role in dendritic spine morphogenesis through membrane-trafficking.

Function:
TRAPPC4 is part of the multisubunit TRAPP (transport protein particle) complex and interacts with SDC2. It may play a role in vesicular transport from endoplasmic reticulum to Golgi. TRAPP proteins are involved in tethering during vesicle transport.

Subunit:
Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Interacts with SDC2 (By similarity).

Subcellular Location:
Endoplasmic reticulum and Golgi Apparatus

Similarity:
Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity).
Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.

Database links:

Entrez Gene: 51399 Human

Entrez Gene: 60409 Mouse

Entrez Gene: 367073 Rat

Omim: 610971 Human

SwissProt: Q9Y296 Human

SwissProt: Q9ES56 Mouse

SwissProt: Q69BT7 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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