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Rabbit Anti-TRAPPC9/Gold Conjugated antibody (bs-16589R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16589R-Gold
英文名稱1 Rabbit Anti-TRAPPC9/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的Nibp蛋白抗體
別    名 1810044A24Rik; 2900005P22Rik; 4632408O18Rik; Ibp; IKBKBBP; Ikk2 binding protein; KIAA1882; MGC4737; MGC4769; mKIAA1882; MRT13; Nibp; NIK and IKK(beta) binding protein; NIK and IKK{beta} binding protein; RGD1309461; T1; Trafficking protein particle complex 9; TPPC9_HUMAN; TRAPP 120 kDa subunit; TRS130; Tularik gene 1 protein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 128kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAPPC9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Function:
TRAPPC9 functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. It may also function in neuronal cells differentiation and play a role in vesicular transport from endoplasmic reticulum to Golgi.

Subunit:
Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Directly interacts with IKBKB and MAP3K14.

Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum. Cytoplasm. Note: Processes and cell bodies of neurons.

Tissue Specificity:
Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and placenta.

DISEASE:
Mental retardation, autosomal recessive 13 (MRT13) [MIM:613192]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the NIBP family.

Database links:

Entrez Gene: 83696 Human

Omim: 611966 Human

SwissProt: Q96Q05 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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