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Rabbit Anti-KLRC3/Gold Conjugated antibody (bs-16781R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16781R-Gold
英文名稱1 Rabbit Anti-KLRC3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的殺傷細(xì)胞凝集素樣受體C亞家族成員3抗體
別    名 Killer cell lectin like receptor subfamily C member 3; KLRC 3; KLRC3; NK cell receptor E; NKG2 E activating NK receptor; NKG2 E; NKG2 E type II integral membrane protein; NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NKG2E activating NK receptor; NKG2E; NKG2E type II integral membrane protein; NKG2E_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞膜受體  淋巴細(xì)胞  t-淋巴細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLRC3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subcellular Location:
Membrane.

Tissue Specificity:
Natural killer cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 3823 Human

Entrez Gene: 58179 Mouse

Entrez Gene: 500338 Rat

Omim: 602892 Human

SwissProt: Q07444 Human

Unigene: 654362 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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