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Rabbit Anti-KCNK4/AP Conjugated antibody (bs-16903R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16903R-AP
英文名稱1 Rabbit Anti-KCNK4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的鉀離子通道蛋白4抗體
別    名 K2p4.1; K2P4.1 potassium channel; KCNK 4; KCNK4_HUMAN; MGC144821; Potassium channel subfamily K member 4; Potassium inwardly rectifying channel subfamily K member 4; TRAAK; TRAAK1; TRAAKt; TWIK related arachidonic acid stimulated potassium channel protein; Two pore K(+) channel KT4.1; Two pore K+ channel KT4.1; Two pore potassium channel KT4.1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNK4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. [provided by RefSeq, Jul 2008]

Function:
KCNK4 belongs to the two pore domain potassium channel family and is an outward rectifying potassium channel. This channel produces rapidly activating and non-inactivating outward rectifier K(+) currents. It is activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Database links:

Entrez Gene: 50801 Human

Entrez Gene: 16528 Mouse

Entrez Gene: 116489 Rat

Omim: 605720 Human

SwissProt: Q9NYG8 Human

SwissProt: O88454 Mouse

Unigene: 647233 Human

Unigene: 12894 Mouse

Unigene: 46453 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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