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Rabbit Anti-GPSN2/AP Conjugated antibody (bs-16301R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16301R-AP
英文名稱(chēng)1 Rabbit Anti-GPSN2/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的突觸糖蛋白2抗體
別    名 2410016D23Rik; A230102P12Rik; TECR_HUMAN; AI173355; D17Ertd178e; Glycoprotein synaptic 2; Gpsn2; Neuroprotective protein 13; SC2; Synaptic glycoprotein SC2; Tecr; TER; Trans 2,3 enoyl CoA reductase.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  糖蛋白  新陳代謝  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPSN2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]

Function:
Microsomal long and very long chain fatty acid elongation uses malonyl CoA as the 2 carbon donor and consists of 4 sequential reactions. GPSN2 catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. (Moon and Horton, 2003 [PubMed 12482854]).

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in most tissues tested. Highly expressed in skeletal muscle.

DISEASE:
Mental retardation, autosomal recessive 14 (MRT14) [MIM:614020]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the steroid 5-alpha reductase family.

Database links:

Entrez Gene: 9524 Human

Entrez Gene: 106529 Mouse

Entrez Gene: 191576 Rat

Omim: 610057 Human

SwissProt: Q9NZ01 Human

SwissProt: Q9CY27 Mouse

SwissProt: Q64232 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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