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Rabbit Anti-SCAI/Gold Conjugated antibody (bs-17260R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-17260R-Gold
英文名稱1 Rabbit Anti-SCAI/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的腫瘤細(xì)胞轉(zhuǎn)移抑制蛋白抗體
別    名 C9orf126; FLJ11758; FLJ36664; MGC120525; MGC120526; MGC120528; NET40; Protein SCAI; SCAI; SCAI_HUMAN; Suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞類型標(biāo)志物  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCAI
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

Function:
Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.

Subunit:
Interacts with DIAPH1 (By similarity). Forms a nuclear ternary complex with MKL1 and SRF.

Subcellular Location:
Membrane. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MKL1.

Similarity:
Belongs to the SCAI family.

Database links:

Entrez Gene: 286205 Human

Entrez Gene: 320271 Mouse

Entrez Gene: 690538 Rat

SwissProt: Q8N9R8 Human

SwissProt: Q8C8N2 Mouse

Unigene: 59504 Human

Unigene: 204836 Mouse

Unigene: 206053 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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