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Rabbit Anti-MTRF1/BF488 Conjugated antibody (bs-17893R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-17893R-BF488
英文名稱(chēng) Rabbit Anti-MTRF1/BF488 Conjugated antibody
中文名稱(chēng) BF488標(biāo)記的線(xiàn)粒體釋放因子1樣蛋白抗體
別    名 HMRF1L; Human mitochondrial release factor 1-like; Mitochondrial release factor 1 like; Mitochondrial translational release factor 1 like; Mitochondrial translational release factor 1-like; mtRF1a; MTRF1L; Peptide chain release factor 1-like, mitochondrial; RF1ML_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  線(xiàn)粒體  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTRF1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Mitochondrial DNA encodes 13 proteins that play essential roles in the respiratory chain, while all proteins involved in mitochondrial translation are encoded by nuclear genes that are imported from the cytoplasm. MTRF1L is a nuclear-encoded protein that functions as a releasing factor that recognizes termination codons and releases mitochondrial ribosomes from the synthesized protein (summary by Nozaki et al., 2008 [PubMed 18429816]).[supplied by OMIM, Nov 2010]

Function:
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Expressed in skeletal muscle (at protein level).

Post-translational modifications:
Methylation of glutamine in the GGQ triplet is conserved from bacteria to mammals.

Similarity:
Belongs to the prokaryotic/mitochondrial release factor family.

Database links:

Entrez Gene: 54516 Human

Omim: 613542 Human

SwissProt: Q9UGC7 Human

Unigene: 225836 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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