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Rabbit Anti-SPCA2/Cy7 Conjugated antibody (bs-17639R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17639R-Cy7
英文名稱1 Rabbit Anti-SPCA2/Cy7 Conjugated antibody
中文名稱 Cy7標記的ATP酶2C2抗體
別    名 AT2C2_HUMAN; ATP2C2; ATPase 2C2; ATPase, Ca++ transporting, type 2C, member 2; Calcium-transporting ATPase type 2C member 2; DKFZp686H22230; hSPCA2; KIAA0703; PMR1; Secretory pathway Ca(2+)-ATPase 2; secretory pathway calcium ATPase 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 103kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPCA2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The family of P-type Ca2+-transport ATPases is made up of three subfamilies: sarco(endo)plasmic-reticulum Ca2+ ATPases (SERCA), plasma- membrane Ca2+ ATPases (PMCA), and secretory-pathway Ca2+ ATPases (SPCA). The SPCA1 protein (encoded for by the ATP2C1 gene) is a Ca2+/ Mn2+-transport ATPase. It localizes to the Golgi apparatus and, together with SERCA2, it is responsible for the ionic milieu in the Golgi lumen. SPCA2 (encoded by the ATP2C2 gene) also localizes to the golgi apparatus and has a higher enzymatic turnover rate than that of SPCA1 while having a high affinity for cytosolic Ca2+. The enzymatic properties of the human SPCA2 enzyme and the restriction of its tissue expression to the gastrointestinal and respiratory tracts, prostate, thyroid, salivary, and mammary glands may, in principle ,define a Ca2+-ATPase pump with a specific physiological role in secretory cells.

Function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.

Subcellular Location:
Membrane.

Tissue Specificity:
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.

Similarity:
Belongs to the cation transport ATPase (P-type) (TC3.A.3) family. Type IIA subfamily.

Database links:

Entrez Gene: 9914 Human

Entrez Gene: 69047 Mouse

Entrez Gene: 171496 Rat

Omim: 613082 Human

SwissProt: O75185 Human

SwissProt: A7L9Z8 Mouse

SwissProt: Q8R4C1 Rat

Unigene: 6168 Human

Unigene: 46251 Mouse

Unigene: 163411 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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