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Rabbit Anti-HSPC210/GSK3beta interaction protein/PE-Cy5 Conjugated antibody (bs-18090R-PE-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-18090R-PE-Cy5
英文名稱1 Rabbit Anti-HSPC210/GSK3beta interaction protein/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的GSK3β相互作用蛋白抗體
別    名 C14ORF129; Chromosome 14 open reading frame 129; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; GSKIP_HUMAN; MGC4945; UPF0279.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cynomolgus Monkey)
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSPC210/GSK3beta interaction protein
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in heart, brain, placenta, liver, skeletal muscle, kidney, testis, lung and pancreas.

Similarity:
Belongs to the UPF0279 family.

Database links:

Entrez Gene: 51527 Human

Entrez Gene: 66787 Mouse

Entrez Gene: 362778 Rat

SwissProt: Q9P0R6 Human

SwissProt: Q8BGR8 Mouse

SwissProt: Q5PPI3 Rat

Unigene: 728153 Human

Unigene: 248019 Mouse

Unigene: 3701 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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