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Rabbit Anti-MON2/Gold Conjugated antibody (bs-17713R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17713R-Gold
英文名稱1 Rabbit Anti-MON2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的MON2蛋白抗體
別    名 mon2; MON2_HUMAN; Protein MON2 homolog; Protein SF21; SF21.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 190kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MON2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
MON2 is a 1,718 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking. Related to the guanine nucleotide exchange factors (GEFs), MON2 shares significant homology with BIG as well as the GBF (Golgi brefeldin A resistance factor) subfamilies of proteins. MON2 acts as a scaffold protein when associated with Dopey-1, a large cytoplasmic protein involved in trafficking between the late golgi and early endosomes. MON2 is homologous to the yeast protein and is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Function:
May be required for traffic between late Golgi and early endosomes.

Similarity:
Belongs to the MON2 family.

Database links:

Entrez Gene: 23041 Human

Entrez Gene: 314894 Rat

SwissProt: Q7Z3U7 Human

Unigene: 389378 Human

Unigene: 154642 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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