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Rabbit Anti-MCT14/Biotin Conjugated antibody (bs-17714R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17714R-Bio
英文名稱1 Rabbit Anti-MCT14/Biotin Conjugated antibody
中文名稱 生物素標記的單羧酸轉運14抗體
別    名 Monocarboxylate transporter 14; FLJ30794; MCT 14; MCT14; Monocarboxylate transporter 14; MOT14_HUMAN; OTTHUMP00000204389; OTTHUMP00000204390; Slc16a14; Solute carrier family 16 (monocarboxylic acid transporters), member 14; Solute carrier family 16 member 14; Solute carrier family 16, member 14 (monocarboxylic acid transporter 14).  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  新陳代謝  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MCT14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT14 (monocarboxylate transporter 14), also known as SLC16A14 (solute carrier family 16, member 14), is a 510 amino acid multi-pass membrane protein that belongs to the MCT family and functions as a proton-linked monocarboxylate transporter, effectively catalyzing the rapid transport of monocarboxylates across the membrane. Multiple isoforms of MCT14 exist due to alternative splicing events.

Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Database links:

Entrez Gene: 151473 Human

Entrez Gene: 71781 Mouse

SwissProt: Q7RTX9 Human

SwissProt: Q8K1C7 Mouse

Unigene: 504317 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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