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Rabbit Anti-MOCS2/BF350 Conjugated antibody (bs-17701R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17701R-BF350
英文名稱1 Rabbit Anti-MOCS2/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的鉬輔因子合成蛋白2抗體
別    名 MCBPE; MOCO1; MOCO1 B; MOCO1B; MOCS 2; MOCS2; MOCS2A; MOCS2B; Molybdenum cofactor biosynthesis protein E; Molybdenum cofactor synthesis 2; Molybdenum cofactor synthesis protein 2 large subunit; molybdenum cofactor synthesis protein 2 small subunit; molybdenum cofactor synthesis protein 2A; Molybdenum cofactor synthesis protein 2B; Molybdopterin synthase; Molybdopterin synthase large subunit; molybdopterin-synthase small subunit; MPT synthase; MPTS; OTTHUMP00000122459; sulfur carrier protein MOCS2A.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MOCS2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]

Function:
The large (MOCS2B) and small (MOCS2A) subunits of molybdopterin synthase are both encoded from the MOCS2 gene by overlapping open reading frames. MOCS2B is the catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. It acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.

Subunit:
Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas.Very low levels are found in lung and peripheral blood leukocytes.

DISEASE:
Molybdenum cofactor deficiency, complementation group B(MOCODB)

Similarity:
Belongs to the MoaE family. MOCS2B subfamily.

Database links:

Entrez Gene: 4338 Human

Omim: 603708 Human

SwissProt: O96007 Human

Unigene: 163645 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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