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Rabbit Anti-MLR2/Gold Conjugated antibody (bs-18198R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-18198R-Gold
英文名稱1 Rabbit Anti-MLR2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的配體依賴核受體共抑制因子抗體
別    名 A630025C20RIK; FLJ38026; KIAA1795; LCoR; Lcor; LCOR_HUMAN; Ligand dependent corepressor; Ligand dependent nuclear receptor corepressor; Ligand-dependent corepressor; Mblk1 related protein 2; Mblk1-related protein 2; MLR2; RP11 175O19.1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MLR2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008]

Function:
May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 HTH psq-type DNA-binding domain.

Database links:

Entrez Gene: 84458 Human

Entrez Gene: 212391 Mouse

Entrez Gene: 365462 Rat

Omim: 607698 Human

SwissProt: Q96JN0 Human

SwissProt: Q6ZPI3 Mouse

Unigene: 729136 Human

Unigene: 398778 Mouse

Unigene: 422910 Mouse

Unigene: 459119 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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