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Rabbit Anti-AKAP1/Gold Conjugated antibody (bs-18605R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-18605R-Gold
英文名稱1 Rabbit Anti-AKAP1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的蛋白激酶A錨定蛋白1抗體
別    名 A kinase anchor protein; A-kinase anchor protein 1; A-kinase anchor protein 149 kDa; AKAP 149; AKAP; Akap1; AKAP1_HUMAN; D-AKAP-1; DAKAP1; Dual specificity A-kinase-anchoring protein 1; mitochondrial; PRKA1; Protein kinase A-anchoring protein 1; Protein kinase A1; S-AKAP84; SAKAP84; Spermatid A-kinase anchor protein 84.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 97kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKAP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]

Function:
Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.

Subcellular Location:
Mitochondrion outer membrane.

Tissue Specificity:
AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.

Similarity:
Contains 1 KH domain.
Contains 1 Tudor domain.

Database links:

Entrez Gene: 8165 Human

Omim: 602449 Human

SwissProt: Q92667 Human

Unigene: 463506 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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