| 產(chǎn)品編號(hào) | bs-18510R-BF488 |
| 英文名稱1 | Rabbit Anti-ZNF366/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的鋅指蛋白366抗體 |
| 別 名 | DC-SCRIPT; DCSCRIPT; Dendritic cell specific transcript; FLJ39796; MGC99415; Zfp366; Zfp366 zinc finger protein 366; Zinc finger protein 366; ZN366_HUMAN; ZNF366. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 85kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF366 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: ZNF366 is a 744 amino acid nuclear protein that contains eleven C2H2-type zinc fingers and is thought to function in transcriptional regulation. The gene encoding ZNF366 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Function: Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases. Subunit: Interacts with ESR1, NRIP1 and CTBP1. Subcellular Location: Nucleus. Similarity: Contains 11 C2H2-type zinc fingers. Database links: Entrez Gene: 167465 Human Entrez Gene: 238803 Mouse Omim: 610159 Human SwissProt: Q8N895 Human Unigene: 370303 Human Unigene: 343207 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
