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Rabbit Anti-MYCBP/PE-Cy3 Conjugated antibody (bs-19140R-PE-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19140R-PE-Cy3
英文名稱1 Rabbit Anti-MYCBP/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的C myc結(jié)合蛋白抗體
別    名 AMY 1; AMY-1; AMY1; Associate of myc 1; C myc binding protein; C-Myc-binding protein; Cmyc binding protein; MYCBP; MYCBP_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  細胞周期蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Chicken, Pig, Cow, Rabbit, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MYCBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]

Function:
May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.

Subcellular Location:
Cytoplasm. Nucleus. Mitochondrion. Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.

Tissue Specificity:
Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.

Similarity:
Belongs to the AMY1 family.

Database links:

Entrez Gene: 26292 Human

Entrez Gene: 539291 Cow

Entrez Gene: 56309 Mouse

Omim: 606535 Human

SwissProt: Q2TBP7 Cow

SwissProt: Q99417 Human

SwissProt: Q9EQS3 Mouse

Unigene: 591506 Human

Unigene: 446553 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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