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Rabbit Anti-DAL1/ EPB41L3/Gold Conjugated antibody (bs-20463R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-20463R-Gold
英文名稱1 Rabbit Anti-DAL1/ EPB41L3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的細(xì)胞骨架4.1蛋白家族DAL1抗體
別    名 Differentially expressed in adenocarcinoma of the lung protein 1; 4.1B; Band 4.1 like protein 3; DAL 1; DAL1; EPB41L3; Erythrocyte membrane protein band 4.1 like 3; HGNC:3380; KIAA0987; E41L3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細(xì)胞骨架  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 96/120kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DAL1/ EPB41L3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors.

Function:
Critical growth regulator in the pathogenesis of meningiomas.

Subunit:
Interacts with CADM1.

Subcellular Location:
Cytoplasm, cytoskeleton

Tissue Specificity:
Expressed at high levels in brain, with lower levels in kidney, intestine, and testis.

Similarity:
ontains 1 FERM domain.

Database links:

Entrez Gene: 23136 Human

Entrez Gene: 13823 Mouse

Entrez Gene: 116724 Rat

Omim: 605331 Human

SwissProt: Q9Y2J2 Human

SwissProt: Q9WV92 Mouse

Unigene: 213394 Human

Unigene: 131135 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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