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Rabbit Anti-RAB39B/AP Conjugated antibody (bs-19715R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19715R-AP
英文名稱1 Rabbit Anti-RAB39B/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的ras基因相關(guān)蛋白RAB39B抗體
別    名 6330580M05Rik; MRX72; OTTHUMP00000024247; OTTMUSP00000020441; RAB39B, member RAS oncogene family; Ras related protein Rab 39B; RAS-associated protein RAB39B; RP13-228J13.2; RP23-252K7.1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAB39B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation. [provided by RefSeq, Aug 2013]

Function:
May be involved in vesicular trafficking. Plays a role in synapse formation.

Subunit:
Interacts (in GTP-bound form) with PICK1 (via PDZ domain); a PICK1 homodimer may allow simultaneous association of RAB39B and GRIA2 to PICK1 which is involved in GRIA2 trafficking.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Highly expressed in the brain.

DISEASE:
Mental retardation, X-linked 72 (MRX72)

Database links:

Entrez Gene: 537560 Cow

Entrez Gene: 116442 Human

Entrez Gene: 67790 Mouse

Entrez Gene: 100328771 Rabbit

Omim: 300774 Human

SwissProt: Q17QU4 Cow

SwissProt: Q96DA2 Human

SwissProt: Q8BHC1 Mouse

Unigene: 55967 Cow

Unigene: 632832 Human

Unigene: 45148 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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