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Rabbit Anti-RASEF/BF350 Conjugated antibody (bs-19733R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19733R-BF350
英文名稱1 Rabbit Anti-RASEF/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的ras基因相關(guān)蛋白R(shí)ab45抗體
別    名 FLJ31614; RAB45; RAB45 member RAS oncogene family; RASEF_HUMAN; RAS and EF hand domain containing; RAS and EF hand domain containing protein; Ras related protein Rab 45.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASEF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012]

Function:
Binds predominantly GDP, and also GTP.

Subcellular Location:
Cytoplasm, perinuclear region.

Tissue Specificity:
Down-regulated in cutaneous melanoma cells but not in breast cancer cells.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 158158 Human

Entrez Gene: 242505 Mouse

Omim: 611344 Human

SwissProt: Q8IZ41 Human

SwissProt: Q5RI75 Mouse

Unigene: 657750 Human

Unigene: 487185 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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