產(chǎn)品編號(hào) | bs-21162R-Gold |
英文名稱(chēng)1 | Rabbit Anti-RASGEF1B/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標(biāo)記的RASGEF1B蛋白抗體 |
別 名 | GPIG4. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Pig, Cow, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 55kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RASGEF1B |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: RASGEF1B (RasGEF Domain Family Member 1B) is a Protein Coding gene. Diseases associated with RASGEF1B include Chromosome 4Q21 Deletion Syndrome. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RASGEF1C. Function: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro). Subunit: Interacts with Ras family proteins (By similarity). Interacts with CCDC124 during cytokinesis. DISEASE: Up-regulated in macrophages stimulated with IFNG, GPI-mucins or bacterial lipopolysaccharides (LPS). Similarity: Contains 1 N-terminal Ras-GEF domain. Contains 1 Ras-GEF domain. Database links: Entrez Gene: 153020 Human SwissProt: Q0VAM2 Human Unigene: 591696 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |